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Pathway Switching Explains the Sharp Response Characteristic of Hypoxia Response Network

Hypoxia induces the expression of genes that alter metabolism through the hypoxia-inducible factor (HIF). A theoretical model based on differential equations of the hypoxia response network has been previously proposed in which a sharp response to changes in oxygen concentration was observed but not...

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Detalhes bibliográficos
Main Authors: Yu, Yihai, Wang, Guanyu, Simha, Rahul, Peng, Weiqun, Turano, Frank, Zeng, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963493/
https://ncbi.nlm.nih.gov/pubmed/17784783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030171
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