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Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum.

Five mutants of Penicillium chrysogenum blocked in penicillin biosynthesis (npe) which are deficient in isopenicillin N-acyltransferase were isolated previously. Three of these mutants, npe6, npe7, and npe8, have been characterized at the molecular level and compared with npe10, a deletion mutant. T...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Fernández, F J, Gutierrez, S, Velasco, J, Montenegro, E, Marcos, A T, Martín, J F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7519594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.16.4941-4948.1994
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