Viability of folA-null derivatives of wild-type (thyA+) Escherichia coli K-12.
Dihydrofolate reductase (the folA gene product) catalyzes the synthesis of tetrahydrofolate, a key methyl donor in many biosynthetic pathways. Loss of folA had been thought to be lethal to wild-type (thyA+) Escherichia coli. Viable folA-null derivatives of thyA+ E. coli were obtained, however, by re...
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| Udgivet i: | J Bacteriol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.3.909-911.1993 |
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