Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease

An unresolved question in cystic fibrosis (CF) research is how mutations of the CF transmembrane conductance regulator, a Cl ion channel, cause airway mucus obstruction leading to fatal lung disease. Recent evidence has linked the CF transmembrane conductance regulator mutation to the onset and pers...

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Bibliographic Details
Main Authors: Li, Jian-Dong, Dohrman, Austin F., Gallup, Marianne, Miyata, Susumu, Gum, James R., Kim, Young S., Nadel, Jay A., Prince, Alice, Basbaum, Carol B.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19623/
https://ncbi.nlm.nih.gov/pubmed/9023366
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