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Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA

Food-ingested foreign DNA is not completely degraded in the gastrointestinal tract of mice. Phage M13mp18 DNA as a test molecule devoid of homology to mouse DNA was pipette-fed to or added to the food supply of mice. The fate of this foreign DNA in the animals was followed by several methods. In 84...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Principais autores: Schubbert, Rainer, Renz, Doris, Schmitz, Birgit, Doerfler, Walter
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 1997
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.961
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