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A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein

Primary DNA damage sensing in mammalian global genome nucleotide excision repair (GG-NER) is performed by the xeroderma pigmentosum group C (XPC)/HR23B protein complex. HR23B and HR23A are human homologs of the yeast ubiquitin-domain repair factor RAD23, the function of which is unknown. Knockout mi...

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Detalhes bibliográficos
Main Authors: Ng, Jessica M.Y., Vermeulen, Wim, van der Horst, Gijsbertus T.J., Bergink, Steven, Sugasawa, Kaoru, Vrieling, Harry, Hoeijmakers, Jan H.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196135/
https://ncbi.nlm.nih.gov/pubmed/12815074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.260003
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