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Mutational uncoupling of the transcriptional activation function of the TyrR protein of Escherichia coli K-12 from the repression function.

The tyrosine repressor (TyrR) protein of Escherichia coli can function either as a transcriptional enhancer or as a repressor. The structural basis for these opposite effects was analyzed in specific tyrR deletion mutants constructed in vitro. The functional behavior of the mutant TyrR proteins was...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Cui, J, Somerville, R L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8416907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.1.303-306.1993
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