Targeted disruption of the mouse αA-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein αB-crystallin

αA-crystallin (αA) and αB-crystallin (αB) are among the predominant proteins of the vertebrate eye lens. In vitro, the α-crystallins, which are isolated together as a high molecular mass aggregate, exhibit a number of properties, the most interesting of which is their ability to function as molecula...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Brady, James P., Garland, Donita, Duglas-Tabor, Yvonne, Robison, W. Gerald, Groome, Anne, Wawrousek, Eric F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023351/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.884
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