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phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development
In this study, we utilize transgenic zebrafish with fluorescently labeled blood vessels to identify and characterize a mutant (y10) that displays specific defects in the formation of arteries, but not veins. We find that y10 encodes phospholipase C gamma-1 (plcg1), a known effector of receptor tyros...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196067/ https://ncbi.nlm.nih.gov/pubmed/12782653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1072203 |
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