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phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development

In this study, we utilize transgenic zebrafish with fluorescently labeled blood vessels to identify and characterize a mutant (y10) that displays specific defects in the formation of arteries, but not veins. We find that y10 encodes phospholipase C gamma-1 (plcg1), a known effector of receptor tyros...

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Detalhes bibliográficos
Main Authors: Lawson, Nathan D., Mugford, Joshua W., Diamond, Brigid A., Weinstein, Brant M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196067/
https://ncbi.nlm.nih.gov/pubmed/12782653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1072203
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