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Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

Hedgehog (Hh) signaling plays a major role in multiple aspects of embryonic development. A key issue is how negative regulation of Hh signaling might contribute to generating differential responses over tens of cell diameters. In cells that respond to Hh, two proteins that are up-regulated are Patch...

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Detalhes bibliográficos
Main Authors: Chuang, Pao-Tien, Kawcak, T'Nay, McMahon, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC195990/
https://ncbi.nlm.nih.gov/pubmed/12569124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1026303
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