Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse

Mouse embryos mutant for the VEGF receptor, VEGFR2, Flk-1, or Kdr, fail to form both endothelial and hematopoietic cells, suggesting a possible role in a common progenitor to both lineages. The transcription factor Tal1 (Scl), is not expressed in Flk1(−/−) embryos, consistent with a downstream role...

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Bibliografske podrobnosti

izdano v:	Genes Dev
Principais autores:	Ema, Masatsugu, Faloon, Patrick, Zhang, Wen Jie, Hirashima, Masanori, Reid, Tammy, Stanford, William L., Orkin, Stuart, Choi, Kyunghee, Rossant, Janet
Format:	Artigo
Jezik:	Inglês
Izdano:	Cold Spring Harbor Laboratory Press 2003
Teme:	Research Paper
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12569129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1049803
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