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Multipotent cell lineages in early mouse development depend on SOX2 function

Each cell lineage specified in the preimplantation mammalian embryo depends on intrinsic factors for its development, but there is also mutual interdependence between them. OCT4 is required for the ICM/epiblast lineage, and at transient high levels for extraembryonic endoderm, but also indirectly th...

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Detalhes bibliográficos
Main Authors: Avilion, Ariel A., Nicolis, Silvia K., Pevny, Larysa H., Perez, Lidia, Vivian, Nigel, Lovell-Badge, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC195970/
https://ncbi.nlm.nih.gov/pubmed/12514105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.224503
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