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Macromolecular Crowding Induces a Molten Globule State in the C-Terminal Domain of Histone H1

We studied the secondary structure of the C-terminal domains of the histone H1 subtypes H1° (C-H1°) and H1t (C-H1t) in the presence of macromolecular crowding agents (Ficoll 70 and PEG 6000) by IR spectroscopy. The carboxyl-terminal domain has little structure in aqueous solution but became extensiv...

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Sonraí Bibleagrafaíochta
Main Authors: Roque, Alicia, Ponte, Inma, Suau, Pedro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biophysical Society 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959549/
https://ncbi.nlm.nih.gov/pubmed/17513371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104513
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