Leukocytes Induce Epithelial to Mesenchymal Transition after Unilateral Ureteral Obstruction in Neonatal Mice

Urinary tract obstruction during renal development leads to tubular apoptosis, tubular atrophy, and interstitial fibrosis. Epithelial to mesenchymal transition (EMT) has been proposed as a key mechanism of myofibroblast accumulation in renal fibrosis. We studied the interplay of leukocyte infiltrati...

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Main Authors: Lange-Sperandio, Bärbel, Trautmann, Agnes, Eickelberg, Oliver, Jayachandran, Aparna, Oberle, Stephan, Schmidutz, Florian, Rodenbeck, Barbara, Hömme, Meike, Horuk, Richard, Schaefer, Franz
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959504/
https://ncbi.nlm.nih.gov/pubmed/17675578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061199
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