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Sustained Secretion of Immunoglobulin by Long-Lived Human Tonsil Plasma Cells

Immunoglobulin-secreting cells comprise both short-lived proliferating plasmablasts and long-lived nonproliferating plasma cells. To determine the phenotype and functional activity of Ig-secreting cells in human lymphoid tissue, we used a tonsillar organ culture model. A significant proportion of Ig...

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Detalhes bibliográficos
Main Authors: van Laar, Jacob M., Melchers, Marc, Teng, Y. K. Onno, van der Zouwen, Boris, Mohammadi, Rozbeh, Fischer, Randy, Margolis, Leonid, Fitzgerald, Wendy, Grivel, Jean-Charles, Breedveld, Ferdinand C., Lipsky, Peter E., Grammer, Amrie C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959503/
https://ncbi.nlm.nih.gov/pubmed/17690187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070005
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