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Salmonella Effector AvrA Regulation of Colonic Epithelial Cell Inflammation by Deubiquitination
AvrA is a newly described bacterial effector existing in Salmonella. Here, we test the hypothesis that AvrA is a deubiquitinase that removes ubiquitin from two inhibitors of the nuclear factor-κB (NF-κB) pathway, IκBα and β-catenin, thereby inhibiting the inflammatory responses of the host. The role...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1959497/ https://ncbi.nlm.nih.gov/pubmed/17690189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070220 |
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