Notch2 Signaling Induces Apoptosis and Inhibits Human MDA-MB-231 Xenograft Growth

Notch functions as an oncogene or tumor inhibitor in various cancers, and decreases in Notch2 expression are associated with increasing grade of human breast cancer. We constitutively activated Notch signaling with intracellular domain (ICD) expression in the human adenocarcinoma line MDA-MB-231. No...

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Main Authors: O’Neill, Christine F., Urs, Sumithra, Cinelli, Christina, Lincoln, Alexis, Nadeau, Robert J., León, Ruth, Toher, Jessica, Mouta-Bellum, Carla, Friesel, Robert E., Liaw, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959488/
https://ncbi.nlm.nih.gov/pubmed/17675579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061029
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