Notch2 Signaling Induces Apoptosis and Inhibits Human MDA-MB-231 Xenograft Growth

Notch functions as an oncogene or tumor inhibitor in various cancers, and decreases in Notch2 expression are associated with increasing grade of human breast cancer. We constitutively activated Notch signaling with intracellular domain (ICD) expression in the human adenocarcinoma line MDA-MB-231. No...

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Bibliografiske detaljer
Main Authors: O’Neill, Christine F., Urs, Sumithra, Cinelli, Christina, Lincoln, Alexis, Nadeau, Robert J., León, Ruth, Toher, Jessica, Mouta-Bellum, Carla, Friesel, Robert E., Liaw, Lucy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2007
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959488/
https://ncbi.nlm.nih.gov/pubmed/17675579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061029
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