Neutrophil Elastase Converts Human Immature Dendritic Cells into Transforming Growth Factor-β1-Secreting Cells and Reduces Allostimulatory Ability

During microbial infection, neutrophils (polymorphonuclear leukocytes; PMNs) activate dendritic cells (DCs). However, early reports illustrated that neutrophil-derived mediators may suppress responses to mitogens. In the present study, we investigated the mechanism used by PMNs to modulate the immun...

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Detalhes bibliográficos
Main Authors: Maffia, Paulo César, Zittermann, Sandra Elizabeth, Scimone, María Lucila, Tateosian, Nancy, Amiano, Nicolás, Guerrieri, Diego, Lutzky, Viviana, Rosso, Diego, Romeo, Horacio Eduardo, Garcia, Verónica E., Issekutz, Andrew C., Chuluyan, H. Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959482/
https://ncbi.nlm.nih.gov/pubmed/17690184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061043
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