Transcriptional repression at a distance through exclusion of activator binding in vivo

The yeast repressor Rme1p acts from distant binding sites to block transcription of the chromosomal IME1 gene. Rme1p can also repress the heterologous CYC1 promoter when Rme1p binding sites are placed 250–300 bp upstream of CYC1 transcriptional activator binding sites (UAS1 and UAS2). Here, in vivo...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Shimizu, Mitsuhiro, Li, Weishi, Shindo, Heisaburo, Mitchell, Aaron P.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1997
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19592/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.3.790
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