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Kindling epileptogenesis in immature rats leads to persistent depressive behavior

Depression is a frequent comorbidity in epilepsy patients. A variety of biological factors may underlie epilepsy-associated depression. We examined whether kindling-induced chronic increase in seizure susceptibility is accompanied by behavioral symptoms of depression. Three week-old Wistar rats unde...

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Bibliographic Details
Main Authors: Mazarati, Andréy, Shin, Don, Auvin, Stéphane, Caplan, Rochelle, Sankar, Raman
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1958957/
https://ncbi.nlm.nih.gov/pubmed/17368107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2007.02.001
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