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Enhanced heterologous gene expression in novel rpoH mutants of Escherichia coli.

Extragenic temperature-resistant suppressor mutants of an rpoD800 derivative of Escherichia coli W3110 were selected at 43.5 degrees C. Two of the mutants were shown to have a phenotype of enhanced accumulation of heterologous proteins. Genetic mapping of the two mutants showed that the mutation con...

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Publicado en:Appl Environ Microbiol
Autores principales: Obukowicz, M G, Staten, N R, Krivi, G G
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1622219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.58.5.1511-1523.1992
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