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Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4(+) T cells via CD40 ligand

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system postulated to be a cell-mediated autoimmune disease in which interferon γ (IFN-γ) plays an important role. There is increased IFN-γ secretion in MS, and IFN-γ administration induces exacerbations of disease. We f...

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Detaylı Bibliyografya
Asıl Yazarlar: Balashov, Konstantin E., Smith, Derek R., Khoury, Samia J., Hafler, David A., Weiner, Howard L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC19559/
https://ncbi.nlm.nih.gov/pubmed/9012830
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