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How gene order is influenced by the biophysics of transcription regulation

What are the forces that shape the structure of prokaryotic genomes: the order of genes, their proximity, and their orientation? Coregulation and coordinated horizontal gene transfer are believed to promote the proximity of functionally related genes and the formation of operons. However, forces tha...

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Detalhes bibliográficos
Main Authors: Kolesov, Grigory, Wunderlich, Zeba, Laikova, Olga N., Gelfand, Mikhail S., Mirny, Leonid A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955771/
https://ncbi.nlm.nih.gov/pubmed/17709750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700672104
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