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Study of active controlled monotherapy used for rheumatoid arthritis, an IL‐6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader‐blinded randomised controlled trial of tocilizumab

OBJECTIVE: To evaluate the ability of tocilizumab (a humanised anti‐IL‐6 receptor antibody) monotherapy to inhibit progression of structural joint damage in patients with RA. METHODS: In a multi‐centre, x ray reader‐blinded, randomised, controlled trial, 306 patients with active RA of <5 years�...

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Autori principali: Nishimoto, Norihiro, Hashimoto, Jun, Miyasaka, Nobuyuki, Yamamoto, Kazuhiko, Kawai, Shinichi, Takeuchi, Tsutomu, Murata, Norikazu, van der Heijde, Désirée, Kishimoto, Tadamitsu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955155/
https://ncbi.nlm.nih.gov/pubmed/17485422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.068064
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