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Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to treatment in systemic sclerosis

OBJECTIVES: To investigate the role of reactive oxygen species (ROS) in the development of the various patterns of systemic sclerosis (SSc) and the mechanisms of ROS production by endothelial cells and fibroblasts. METHODS: Production of hydrogen peroxide (H(2)O(2)), nitric oxide (NO) and cellular p...

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Autori principali: Servettaz, A, Guilpain, P, Goulvestre, C, Chéreau, C, Hercend, C, Nicco, C, Guillevin, L, Weill, B, Mouthon, L, Batteux, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955145/
https://ncbi.nlm.nih.gov/pubmed/17363403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.067504
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