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Changes in bone remodelling and antifracture efficacy of intermittent bisphosphonate therapy: implications from clinical studies with ibandronate

Bisphosphonates reduce the rate of bone resorption and bone remodelling. Given daily, they decrease the risk of fractures in postmenopausal osteoporosis. When bisphosphonates were given at extended drug‐free intervals this antifracture efficacy was generally not seen. This may be due to the differen...

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Detalhes bibliográficos
Main Authors: Papapoulos, S E, Schimmer, R C
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955119/
https://ncbi.nlm.nih.gov/pubmed/17277001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.064931
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