Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti‐citrulline autoreactivity is associated with up regulation of proinflammatory cytokines

OBJECTIVES: To identify peripheral blood autoantibody and cytokine profiles that characterise clinically relevant subgroups of patients with early rheumatoid arthritis using arthritis antigen microarrays and a multiplex cytokine assay. METHODS: Serum samples from 56 patients with a diagnosis of rheu...

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Detalhes bibliográficos
Main Authors: Hueber, Wolfgang, Tomooka, Beren H, Zhao, Xiaoyan, Kidd, Brian A, Drijfhout, Jan W, Fries, James F, van Venrooij, Walther J, Metzger, Allan L, Genovese, Mark C, Robinson, William H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954670/
https://ncbi.nlm.nih.gov/pubmed/16901957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.054924
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