T cell responses to a non‐glycosylated epitope predominate in type II collagen‐immunised HLA‐DRB1*0101 transgenic mice

AIM: To study collagen‐induced arthritis in human leucocyte antigen (HLA)‐DR1 transgenic mice lacking endogenous major histocompatibility complex class II molecules (MHC‐II) and to determine T cell specificity against the arthritogenic CII(259–273) epitope of type II collagen either unmodified or po...

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Detalhes bibliográficos
Main Authors: von Delwig, Alexei, Altmann, Daniel M, Charlton, Fraser G, McKie, Norman, Isaacs, John D, Holmdahl, Rikard, Robinson, John H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954639/
https://ncbi.nlm.nih.gov/pubmed/17114189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.061945
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