Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis

BACKGROUND: Several clinical and experimental lines of evidence suggest that leucotriene B4 (LTB4), an arachidonic acid derivative with potent proinflammatory properties, plays a key role in the pathophysiology of rheumatoid arthritis (RA). OBJECTIVE: To evaluate the efficacy and safety of BIIL 284,...

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Detalhes bibliográficos
Main Authors: Díaz‐González, Federico, Alten, Rieke H E, Bensen, William G, Brown, Jacques P, Sibley, John T, Dougados, Maxime, Bombardieri, Stefano, Durez, Patrick, Ortiz, Pablo, de‐Miquel, Gonzalo, Staab, Alexander, Sigmund, Ralf, Salin, Laurence, Leledy, Caroline, Polmar, Stephen H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954613/
https://ncbi.nlm.nih.gov/pubmed/17170051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.062554
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