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Major proteinase movement upon stable serpin–proteinase complex formation

To determine whether formation of the stable complex between a serpin and a target proteinase involves a major translocation of the proteinase from its initial position in the noncovalent Michaelis complex, we have used fluorescence resonance energy transfer to measure the separation between fluores...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Stratikos, Efstratios, Gettins, Peter G. W.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1997
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012804/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.453
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