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Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis

The enzymes of the shikimate pathway are attractive targets for new-generation antimicrobial agents. The first step of this pathway is catalysed by 3-deoxy-d-­arabino-heptulosonate-7-phosphate (DAH7P) synthase and involves the condensation of phosphoenolpyruvate (PEP) and erythrose 4-phosphate (E4P)...

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Main Authors: Webby, Celia J., Lott, J. Shaun, Baker, Heather M., Baker, Edward N., Parker, Emily J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: International Union of Crystallography 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952427/
https://ncbi.nlm.nih.gov/pubmed/16511053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105007931
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