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Phosphorylation of Rga2, a Cdc42 GAP, by CDK/Hgc1 is crucial for Candida albicans hyphal growth

Cyclin-dependent kinases (CDKs) control yeast morphogenesis, although how they regulate the polarity machinery remains unclear. The dimorphic fungus Candida albicans uses Cdc28/Hgc1, a CDK/cyclin complex, to promote persistent actin polarization for hyphal growth. Here, we report that Rga2, a GTPase...

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Detalhes bibliográficos
Main Authors: Zheng, Xin-De, Lee, Raymond Teck Ho, Wang, Yan-Ming, Lin, Qi-Shan, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952229/
https://ncbi.nlm.nih.gov/pubmed/17673907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601814
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