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J-protein co-chaperone Sis1 required for generation of [RNQ(+)] seeds necessary for prion propagation
Yeast prions are protein-based genetic elements capable of self-perpetuation. One such prion, [RNQ(+)], requires the J-protein Sis1, an Ssa Hsp70 co-chaperone, as well as the AAA+ ATPase, Hsp104, for its propagation. We report that, upon depletion of Sis1, as well as upon inactivation of Hsp104, Rnq...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952226/ https://ncbi.nlm.nih.gov/pubmed/17673909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601811 |
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