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Ligand-Independent Regulation of Transforming Growth Factor β1 Expression and Cell Cycle Progression by the Aryl Hydrocarbon Receptor

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxic effects of its xenobiotic ligands and acts as an environmental checkpoint during the cell cycle. We expressed stably integrated, Tet-Off-regulated AHR variants in fibroblasts from AHR-null mice to...

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Hlavní autoři: Chang, Xiaoqing, Fan, Yunxia, Karyala, Saikumar, Schwemberger, Sandy, Tomlinson, Craig R., Sartor, Maureen A., Puga, Alvaro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952156/
https://ncbi.nlm.nih.gov/pubmed/17606626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00323-07
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