Arkadia Activates Smad3/Smad4-Dependent Transcription by Triggering Signal-Induced SnoN Degradation

E3 ubiquitin ligases play important roles in regulating transforming growth factor β (TGF-β)/Smad signaling. Screening of an E3 ubiquitin ligase small interfering RNA library, using TGF-β induction of a Smad3/Smad4-dependent luciferase reporter as a readout, revealed that Arkadia is an E3 ubiquitin...

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Bibliografiske detaljer
Main Authors: Levy, Laurence, Howell, Michael, Das, Debipriya, Harkin, Sean, Episkopou, Vasso, Hill, Caroline S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952153/
https://ncbi.nlm.nih.gov/pubmed/17591695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00664-07
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