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Aquaporin 7 Is a β-Cell Protein and Regulator of Intraislet Glycerol Content and Glycerol Kinase Activity, β-Cell Mass, and Insulin Production and Secretion

To investigate if intracellular glycerol content plays a role in the regulation of insulin secretion in pancreatic β cells, we studied the expression of the glycerol channels, or aquaglyceroporins, encoded by the aquaporin 3 (Aqp3), Aqp7, and Aqp9 genes in mouse islets. We found expression of Aqp7 o...

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Detalhes bibliográficos
Main Authors: Matsumura, Kazuhiro, Chang, Benny Hung-Junn, Fujimiya, Mineko, Chen, Weiqin, Kulkarni, Rohit N., Eguchi, Yutaka, Kimura, Hiroshi, Kojima, Hideto, Chan, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952143/
https://ncbi.nlm.nih.gov/pubmed/17576812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00384-07
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