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Conserved Regions from Neisseria gonorrhoeae Pilin Are Immunosilent and Not Immunosuppressive

PilE is the primary subunit of type IV pili from Neisseria gonorrhoeae and contains a surface-exposed hypervariable region thought to be one feature of pili that has prevented development of a pilin-based vaccine. We have created a three-dimensional structure-based antigen by replacing the hypervari...

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Bibliografske podrobnosti
Main Authors: Hansen, Johanna K., Demick, Karen P., Mansfield, John M., Forest, Katrina T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951979/
https://ncbi.nlm.nih.gov/pubmed/17562775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02015-06
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