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Overproduction of Penicillin-Binding Protein 2 and Its Inactive Variants Causes Morphological Changes and Lysis in Escherichia coli

Penicillin-binding protein 2 (PBP 2) has long been known to be essential for rod-shaped morphology in gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa. In the course of earlier studies with P. aeruginosa PBP 2, we observed that E. coli was sensitive to the overexpression...

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Autors principals: Legaree, Blaine A., Adams, Calvin B., Clarke, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951868/
https://ncbi.nlm.nih.gov/pubmed/17513478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00207-07
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