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Overproduction of Inactive Variants of the Murein Synthase PBP1B Causes Lysis in Escherichia coli

Penicillin-binding protein 1B (PBP1B) of Escherichia coli is a bifunctional murein synthase containing both a transpeptidase domain and a transglycosylase domain. The protein is present in three forms (α, β, and γ) which differ in the length of their N-terminal cytoplasmic region. Expression plasmid...

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Detalhes bibliográficos
Main Authors: Meisel, Ute, Höltje, Joachim-Volker, Vollmer, Waldemar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193747/
https://ncbi.nlm.nih.gov/pubmed/12949085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.18.5342-5348.2003
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