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A Small Conserved Domain of Drosophila PERIOD Is Important for Circadian Phosphorylation, Nuclear Localization, and Transcriptional Repressor Activity
We identify in this study a 27-amino-acid motif which is conserved between the Drosophila melanogaster period protein (PER) and the three mammalian PERs. Characterization of PER lacking this motif (PERΔ) shows that it is important for phosphorylation of Drosophila PER by casein kinase Iɛ (CKIɛ; doub...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951469/ https://ncbi.nlm.nih.gov/pubmed/17452453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02338-06 |
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