Porcine Arterivirus Attachment to the Macrophage-Specific Receptor Sialoadhesin Is Dependent on the Sialic Acid-Binding Activity of the N-Terminal Immunoglobulin Domain of Sialoadhesin

The sialic acid-binding lectin sialoadhesin (Sn) is a macrophage-restricted receptor for porcine reproductive and respiratory syndrome virus (PRRSV). To investigate the importance of pSn sialic acid-binding activity for PRRSV infection, an R(116)-to-E mutation was introduced in the predicted sialic...

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Bibliographische Detailangaben
Hauptverfasser: Delputte, Peter L., Van Breedam, Wander, Delrue, Iris, Oetke, Cornelia, Crocker, Paul R., Nauwynck, Hans J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951444/
https://ncbi.nlm.nih.gov/pubmed/17567703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00569-07
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