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Cathepsin B Mediates Cleavage of Herpes Simplex Virus Type 1 Origin Binding Protein (OBP) To Yield OBPC-1, and Cleavage Is Dependent upon Viral DNA Replication

Although the seven viral proteins required for herpes simplex virus type 1 (HSV-1) DNA replication have been identified, the mechanism by which viral DNA synthesis is regulated is unclear. HSV-1 DNA replication is thought to occur in two stages: origin-dependent DNA replication (stage I) mediated by...

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מידע ביבליוגרפי
Main Authors: Link, Malen A., Silva, Laurie A., Schaffer, Priscilla A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951438/
https://ncbi.nlm.nih.gov/pubmed/17553869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00676-07
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