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Hepatitis B Virus Maturation Is Sensitive to Functional Inhibition of ESCRT-III, Vps4, and γ2-Adaptin

Hepatitis B virus (HBV) is an enveloped DNA virus that presumably buds at intracellular membranes of infected cells. HBV budding involves two endocytic host proteins, the ubiquitin-interacting adaptor γ2-adaptin and the Nedd4 ubiquitin ligase. Here, we demonstrate that HBV release also requires the...

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Autors principals: Lambert, Carsten, Döring, Tatjana, Prange, Reinhild
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951427/
https://ncbi.nlm.nih.gov/pubmed/17553870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00479-07
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