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Human Cytomegalovirus Gene Expression Is Silenced by Daxx-Mediated Intrinsic Immune Defense in Model Latent Infections Established In Vitro

In addition to productive lytic infections, herpesviruses such as human cytomegalovirus (HCMV) establish a reservoir of latently infected cells that permit lifelong colonization of the host. When latency is established, the viral immediate-early (IE) genes that initiate the lytic replication cycle a...

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Main Authors: Saffert, Ryan T., Kalejta, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951389/
https://ncbi.nlm.nih.gov/pubmed/17596307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00827-07
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