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Lambda Interferon (IFN-λ) in Serum Is Decreased in Hantavirus-Infected Patients, and In Vitro-Established Infection Is Insensitive to Treatment with All IFNs and Inhibits IFN-γ-Induced Nitric Oxide Production

Hantaviruses, causing hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), are known to be sensitive to nitric oxide (NO) and to pretreatment with type I and II interferons (alpha interferon [IFN-α]/IFN-β and IFN-γ, respectively). Elevated serum levels of NO a...

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Autores principales: Stoltz, Malin, Ahlm, Clas, Lundkvist, Åke, Klingström, Jonas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951347/
https://ncbi.nlm.nih.gov/pubmed/17522204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00415-07
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