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Lambda Interferon (IFN-λ) in Serum Is Decreased in Hantavirus-Infected Patients, and In Vitro-Established Infection Is Insensitive to Treatment with All IFNs and Inhibits IFN-γ-Induced Nitric Oxide Production

Hantaviruses, causing hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), are known to be sensitive to nitric oxide (NO) and to pretreatment with type I and II interferons (alpha interferon [IFN-α]/IFN-β and IFN-γ, respectively). Elevated serum levels of NO a...

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Bibliographic Details
Main Authors: Stoltz, Malin, Ahlm, Clas, Lundkvist, Åke, Klingström, Jonas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951347/
https://ncbi.nlm.nih.gov/pubmed/17522204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00415-07
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