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Natural Variation in the V3 Crown of Human Immunodeficiency Virus Type 1 Affects Replicative Fitness and Entry Inhibitor Sensitivity

Natural polymorphisms in the heterogeneous human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein may have an impact on both sensitivity to entry inhibitors and viral replicative fitness. Of significant interest is variation in the V3 crown due to its involvement in direct engagement with...

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Hlavní autoři: Lobritz, Michael A., Marozsan, Andre J., Troyer, Ryan M., Arts, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951322/
https://ncbi.nlm.nih.gov/pubmed/17522224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02739-06
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