Adaptation of Borna Disease Virus to New Host Species Attributed to Altered Regulation of Viral Polymerase Activity

Borna disease virus (BDV) can persistently infect the central nervous system of a broad range of mammalian species. Mice are resistant to infections with primary BDV isolates, but certain laboratory strains can be adapted to replicate in mice. We determined the molecular basis of adaptation by study...

Full description

Saved in:
Bibliographic Details
Main Authors: Ackermann, Andreas, Staeheli, Peter, Schneider, Urs
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951315/
https://ncbi.nlm.nih.gov/pubmed/17522214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00334-07
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items