Neisserial Outer Membrane Vesicles Bind the Coinhibitory Receptor Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 1 and Suppress CD4(+) T Lymphocyte Function

Pathogenic Neisseria bacteria naturally liberate outer membrane “blebs,” which are presumed to contribute to pathology, and the detergent-extracted outer membrane vesicles (OMVs) from Neisseria meningitidis are currently employed as meningococcal vaccines in humans. While the composition of these ve...

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Detalhes bibliográficos
Main Authors: Lee, Hannah S. W., Boulton, Ian C., Reddin, Karen, Wong, Henry, Halliwell, Denise, Mandelboim, Ofer, Gorringe, Andrew R., Gray-Owen, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951172/
https://ncbi.nlm.nih.gov/pubmed/17620353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00222-07
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