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Effects of Intranasal Administration of a Leptin-Secreting Lactococcus lactis Recombinant on Food Intake, Body Weight, and Immune Response of Mice

Leptin is an adipocyte-derived pleiotropic hormone that modulates a large number of physiological functions, including control of body weight and regulation of the immune system. In this work, we show that a recombinant strain of the food-grade lactic acid bacterium Lactococcus lactis (LL-lep) can p...

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Detalhes bibliográficos
Main Authors: Bermúdez-Humarán, Luis G., Nouaille, Sébastien, Zilberfarb, Vladimir, Corthier, Gérard, Gruss, Alexandra, Langella, Philippe, Issad, Tarik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950963/
https://ncbi.nlm.nih.gov/pubmed/17601816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00295-07
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